South San Francisco

The San Francisco Peninsula

Located just north of the San Francisco International Airport and bordering the San Francisco Bay, South San Francisco, also known as "South City" to locals, offers visitors numerous activities, restaurants, and places to stay.

South San Francisco is recognized as the "Biotech Capital of the World" (ever heard of Genentech?), and the location's accessibility is also a major draw. The city offers numerous hotel options and excellent public transportation to San Francisco and the Bay Area. BART (Bay Area Rapid Transit) is available at the South San Francisco Station and Ferry Service is available at the Oyster Point Marina.


Exterior of SAP Building overlooking the Oyster Point Marina in South San Francisco

Photo courtesy of City of SSF by Billy Hustace Photography


When Karl the Fog burns off in the early afternoon, there are plenty of exciting things to do in South Francisco, including hiking the renowned Sign Hill Park or exploring the scenic Oyster Point Park and Marina. Want to test your wine knowledge? Look no further! Founded by Master Sommelier and Certified Wine Educator David Glancy (there are only 12 of these people in the world!) San Francisco Wine School offers visitors of any level to come and learn about the nuances of this fine craft.


Downtown South San Francisco

Photo courtesy of City of SSF by Billy Hustace Photography

South San Francisco Hotels


South San Francisco's hotel offerings are equally impressive, each with its own unique character and charm.  As the "Biotech Capital of the World", it is expected that many of the South San Francisco hotels offer unparalleled meeting space such as the AC Hotel SFO/Oyster Point Waterfront or the Embassy Suites SFO. Attending a meeting at the South San Francisco Conference Center? Nearby hotels such as the Best Western Plus Grosvenor, the Four Points by Sheraton, or the Holiday Inn SF International Airport offer convenient accommodations minutes away from the Conference Center. If you’re looking for a place that’s just a few steps from the bay waterfront, take a look at the Courtyard SFO or the Residence Inn SFO at Oyster Point Waterfront. Looking for more options? View more hotels in South San Francisco and start planning your trip to this remarkable city!

South San Francisco Restaurants


If you’re craving Island-inspired plates and cocktails at a reasonable price you can’t pass up Hula Hoops! Looking for something on the lighter side? The AC Waterfront Lounge offers evening tapas and local beer and wine selections with a gorgeous view of the bay. Looking to unwind with the city's best happy hour? South San Francisco's Houlihan's restaurant provides a great dining experience.